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Investing dark biodiversity

Containing the spread of deadly superbugs

DEINOVE is a French biotechnology company pioneering the exploration of a new domain of life, unexplored at 99.9%: the microbial dark matter [1]. By revealing the metabolic potential of rare bacteria or still classified as uncultivable, it tackles a global health and economic challenge [2] : antimicrobial resistance. The new therapies discovered and developed by DEINOVE (antibiotics, antifungals, antivirals and antiparasitics) target superbugs (microbes that resist to one or several antimicrobials) that cause life-threatening infections which are now spreading at high speed.

This breakthrough approach gave birth to one of the World first specialized micro-biotechnology platforms and a unique collection of 10,000 rare strains and thousands of bacterial extracts. Nowadays, DEINOVE is conducting several development programs, of which its first antibiotic candidate is currently evaluated in a Phase II clinical trial in severe Clostridioides difficile infections, one of the World primary emergencies. The Company has also developed new bacterial micro-factories that address the other issue in the race against antimicrobial resistance: the industrial production of these rare and low concentrated compounds with often too complex chemical structures to be generated by chemical synthesis.
Based at the heart of the Euromédecine park in Montpellier, DEINOVE is listed on EURONEXT GROWTH® (ALDEI) since 2010. The Company has 50 employees and leans on a world class network of academic, technological, industrial and institutional partners.

 

[1]Kenneth J. Locey and Jay T. Lennon, Scaling laws predict global microbial diversity, PNAS May 24, 2016 113 (21) 5970-5975

[2]Tackling Drug-Resistant Infections Globally: Final Report And Recommendations The Review On Antimicrobial Resistance Chaired By Jim O’neill. Welcome Trust and the UK Department of Health.May 2016

 

Discover what DEINOVE is doing in the search for new antimicrobials