Assessing the safety of the lead compounds

The Cell biology platform is used to conduct pharmacokinetic trials and check safety on human cells. 

As part of the pharmaceutical activities, this platform has several objectives:

  • Characterize pharmacokinetic parameters (ADME profile: absorption, distribution, metabolism, and excretion) of the lead compounds to predict the evolution of the drug candidate in the organism,
  • Check for cytotoxicity and haemolytic effect: monitor safety.

This plateform uses high-technology cell biology and biochemistry methods, as well as high-throughput microscopy methods.

 

Key features

 

Automated high-content screening

High-sensitivity screening